Persistent ST Elevation and New Regional Wall Motion Abnormalities without Evidence of Coronary Artery Obstruction after Surgical Repair of an Endocarditic Aortic Valve

Erik R. Perschau DO and Yong G. Peng MD, PhD
Department of Anesthesiology, University of Florida, Gainesville, Florida

ABSTRACT
Perioperative myocardial infarction is an important complication of adult cardiac surgery. Its cause typically relates to underlying coronary disease or intraoperative factors such as spasm, emboli, coronary thrombosis. Intraoperative modalities commonly employed to diagnose myocardial ischemia include the electrocardiogram, transesophageal echocardiography (TEE), and the pulmonary artery catheter. Presence of regional wall motion abnormalities (RWMA) in TEE is considered the most sensitive method of detecting intraoperative myocardial ischemia.1,2 We present a case that highlights important limitations of these diagnostic modalities.

A 53 year old male with bacterial endocarditis presented for surgical repair/replacement of the infected aortic valve. Preoperative coronary andiography demonstrated normal coronary arteries, normal contractile function of all wall segments and progressive aortic insufficiency. After debridement and repair of his native valve the patient developed persistent ST segment elevation and regional wall motion abnormalities consistent with acute myocardial infarction in the territory of the right coronary artery. Inspection of the right coronary showed no abnormalities. Therefore, coronary angiography was repeated immediately after wound closure. Again the coronaries were found to be normal and widely patent. The patient’s ST-segment elevations resolved along with the RWMA over the course of the next two days. Serologic markers of myocardial ischemia were abnormal postoperatively. Their values were in excess of those seen after uneventful cardiac surgery, but less than those characteristic of perioperative myocardial infarction.

In summary, we present a case wherein clinical scenario, EKG, and TEE pointed towards an acute myocardial infarction, although angiography repeatedly showed unobstructed coronaries. This case highlights the diagnostic help provided by EKG and TEE as well as the inherent limitations of these monitors in delineating the etiology of impaired cardiac function.

References:
1. Selbst et al, “Myocardial Ischemia Monitoring,” International Anesthesiology Clinics 2002;40:133-46
2. Comunale et al, “The Concordance of Intraopreative Left Ventricular Wall Motion Abnormalities and Electrocardiographic ST Segment Changes,” Anesthesiology 1998 April;88(4):945-54

 

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2000 - Cole, Deckinga, Denson, Fuchs, Maples, Naik, Robicsek, R. Zhang

2001 - Denney, Fuchs, Liem, Palacios, Rajasekaran, Rice, Sessions

2002
- Fuchs, Li #1, Li #2, Mayo, Ozcan, Tagalakis,

2003 - Barotti, Barry, Ozcan, Patel, Robinson, Swinney, Tran, van der Heusen , Walters

2004 - Abbasian, Bird, Cahill, Chang, Dahleen, Durret, Horowitz, Perschau, Robinson, Muehlschlegel, Santiago, Velez, Wendling

2005 case reports - Bauernfeind, Cummens, Dagen, Dobija, Yavas

2006 - Book, Chen, Covington, Eisenman, Ficarotta, Hyde, Jordan, Le, Lesko, Moorjani, Muehlschlegel, Seghal, Stine, Tilman