Anesthetic management for Cesarean section in term parturient with a ruptured intracranial AV malformation

Linda T Le, MD and A Wendling, MD
Department of Anesthesiology, University of Florida, Gainesville, Florida

Rupture of an arterio-venous malformation (AVM) during pregnancy is a rare (5:10,000 parturients) but potentially fatal occurrence with a mortality rate that exceeds 30%. Ruptures have been documented in the second and third trimester of pregnancy with a 30% rate of re-bleeding. For a parturient with an AVM, both the delivery and the attendant anesthesia need to be managed with the goal of minimizing transmural pressure changes in the AVM.

A parturient with a subarachnoid hemorrhage secondary to a left cerebellar AVM presented at 38 weeks gestational age for cesarean section prior to definitive neurosurgical treatment of the AVM. The patient presented one day prior with headaches, nausea and vomiting. CT angiogram revealed a left inferior cerebellar intraparenchymal hemorrhage with moderate hydrocephalus. The patient’s past medical history was remarkable for depression and a previous cesarean section for uterine fibroids. A joint decision by the anesthesia, neurosurgical and obstetric department was made to proceed with cesarean section prior to embolization versus surgical resection of the AVM. We utilized a combined spinal epidural technique for the delivery of the fetus to avoid the potential swings in blood pressure with emergence and to allow for awake neurologic monitoring. Surgery proceeded uneventfully and a healthy baby boy was delivered. The patient fully recovered neurologic function of her lower extremities and subsequently underwent successful AVM resection 3 days after cesarean section.

In the patient with an untreated AV malformation, anesthetic management is complicated by the risk of rebleeding and its associated mortality. Whether regional or general anesthesia is utilized, the anesthesiologist needs to consider the risks, benefits and limitations of each. We review the associated cerebral and systemic hemodynamic changes associated with both techniques.

 

Department Patents

Faculty Research

GAARRC Abstracts


2000 - Cole, Deckinga, Denson, Fuchs, Maples, Naik, Robicsek, R. Zhang

2001 - Denney, Fuchs, Liem, Palacios, Rajasekaran, Rice, Sessions

2002
- Fuchs, Li #1, Li #2, Mayo, Ozcan, Tagalakis,

2003 - Barotti, Barry, Ozcan, Patel, Robinson, Swinney, Tran, van der Heusen , Walters

2004 - Abbasian, Bird, Cahill, Chang, Dahleen, Durret, Horowitz, Perschau, Robinson, Muehlschlegel, Santiago, Velez, Wendling

2005 case reports - Bauernfeind, Cummens, Dagen, Dobija, Yavas

2006 - Book, Chen, Covington, Eisenman, Ficarotta, Hyde, Jordan, Le, Lesko, Moorjani, Muehlschlegel, Seghal, Stine, Tilman