Coronary Artery Aneurysm: A Case Report

Amy Deckinga, M.D.
The Department of Anesthesiology
University of Florida College of Medicine

Aneurysmal dilation of the coronary arteries is a rare occurrence. When it does happen, the most common cause is atherosclerosis. Of the coronary vessels, the least frequently involved is the left main coronary artery (LMA). A case is presented of LMA aneurysm associated with severe atherosclerotic coronary disease.
V.B. is a 51 year old male with a history of coronary artery disease and a previous myocardial infarction in 1994. He had stable angina from 1994 until 1999, when he began having increasing frequency of angina. He underwent an exercise treadmill test that elicited angina and ST depression. He then had an adenosine thallium study that showed inferolateral infarct and anterolateral ischemia. He was admitted for cardiac catheterization.
The rest of his past medical history includes type 2 diabetes mellitus, hypertension, hypercholesterolemia, schizophrenia, post-traumatic stress disorder, and a gun shot wound to the right ankle which subsequently became infected and resulted in a right above knee amputation. He has no history of drug allergies and his medications include aspirin, metoprolol, glyburide, simvastatin, and isordil. He has a sixty pack-year smoking history and quit in 1994. Family history is positive for coronary artery disease. On physical examination, his blood pressure was 117/77 mmHg, pulse was 70 beats per minute, auscultation revealed clear lung fields and normal heart sounds. Electrocardiogram showed sinus rhythm at a rate of 67 and q waves in the inferior leads.
Cardiac catheterization revealed an aneurysm of the LMA measuring 2.5cm x 2cm. In addition, he had diffuse three vessel disease including 95% osteal left anterior descending, 100% proximal circumflex, and 90% mid and distal right coronary artery obstructions. At the time of cardiac catheterization an intra-aortic balloon pump was placed and he was started on a heparin drip. The cardio-thoracic surgery service was consulted and he was scheduled for operative intervention the following day.
At operation he underwent four vessel coronary artery bypass grafting and ligation of the LMA. The aneurysm was visualized on trans-esophageal echocardiogram performed prior to incision. Aortic cross-clamp time was 79 minutes with a total cardio-pulmonary bypass (CPB) time of 140 minutes, and moderate hypothermia to 28 degrees. After re-warming, successful cardioversion to normal sinus rhythm was performed. He was weaned off of CPB and remained hemodynamically stable. Post-operatively he was transferred to the cardio-thoracic intensive care unit. He had an uneventful recovery and was discharged home in stable condition.
In summary, this case represents a LMA aneurysm in association with severe atherosclerotic heart disease. The patient underwent successful 4 vessel bypass grafting and ligation of the LMA.

References:
1) Angiology 1999;50:417-20 3) Am Heart J 1992;123:222-24
2) Am J of Cardiol 1999;83:1290-93 4) J of Cardiovasc Surg 1994;35:311-314

 


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2000 - Cole, Deckinga, Denson, Fuchs, Maples, Naik, Robicsek, R. Zhang

2001 - Denney, Fuchs, Liem, Palacios, Rajasekaran, Rice, Sessions

2002
- Fuchs, Li #1, Li #2, Mayo, Ozcan, Tagalakis,

2003 - Barotti, Barry, Ozcan, Patel, Robinson, Swinney, Tran, van der Heusen , Walters

2004 - Abbasian, Bird, Cahill, Chang, Dahleen, Durret, Horowitz, Perschau, Robinson, Muehlschlegel, Santiago, Velez, Wendling

2005 case reports - Bauernfeind, Cummens, Dagen, Dobija, Yavas

2006 - Book, Chen, Covington, Eisenman, Ficarotta, Hyde, Jordan, Le, Lesko, Moorjani, Muehlschlegel, Seghal, Stine, Tilman