From the home page of the New York Times. A quick read on a topic of great importance for breast cancer survivors. Vital Signs – Pain Often Lasts Long After Breast Cancer Surgery, Study Finds – NYTimes.com.
Who knew that anesthesia had such an integral role in the modern placebo? A simply fantastic introduction to the topic, from a slightly uncharacteristic source.
Nearly 60% of women experienced severe pain following breast cancer surgery in this retrospective study. Such pain remained for nearly 1 in 4 women at 1 month after surgery, and nearly 1 in 10 at 6-12 months following surgery.
Non-White race, obesity, and high PACU opioid use were correlated with increased pain at 1 month. Systolic hypertension and older age were correlated with lower pain scores.
There is no mention of the role of regional anesthesia in this study.
Very interesting.
Prolonged use of high-dose morphine impairs angiog…[Anesth Analg. 2008] – PubMed Result
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Pre-treatment with morphine does not prevent the development of remifentanil-induced hyperalgesia. [Can J Anaesth. 2008] – PubMed Result
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Interesting. This study took 2 groups of children undergoing scoliosis surgery under remifentanil, starting dose well within the usual range. One group received morphine (0.15mg/kg) prior to the remi, the other group saline. The group which received the [...]
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