Asides
NEJM — Outcome Reporting in Industry-Sponsored Trials of Gabapentin for Off-Label Use
Worth reading. With all of the relatively recent literature on gabapentin for acute pain, we should remember this bit of history. NEJM — Outcome Reporting in Industry-Sponsored Trials of Gabapentin for Off-Label Use.
Test
Test
Gabapentin and Ketamine for TAH.
Ok, that’s a lot of gabapentin, at least compared to our use. Ketamine dosing a bit on the low end as the authors point out. However, no difference in sedation post-operatively!. Also, minimal differences in opioid side-effect profile despite decreased opioid consumption. Wished they would have had a fourth group combining ketamine and gabapentin.
via A&A [...]
The Effect of Perioperative IV Lidocaine on Post-Op Pain and Immune Function
What’s nice about this study is the control group: PCEA! The differences in pain scores were statistically different but of questionable clinical difference. Another study with incremental pain improvements, but importantly reflecting non-incremental changes in perioperative stress response. Also note the higher pain scores despite increased PCEA volume and intra-op opioid use (although, this could [...]
Cervical Plexus Block Provides Postoperative Analgesia After Clavicle Surgery — Choi et al. 100 (5): 1542 — Anesthesia & Analgesia
This question seems to come up a fair amount. Just a letter to the editor, but a nice dermatomal mapping is attached. Not so sure about the classic approach to the deep cervical plexus; this is a near-root structure. No needle description is give. I would hope it was large and non-sharp, with appropriate aspiration/open-air [...]
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